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Rethinking Platinum Anticancer Drug Design: Towards Targeted and Immuno-chemothe

Description: Rethinking Platinum Anticancer Drug Design: Towards Targeted and Immuno-chemotherapeutic Approaches by Daniel Yuan Qiang Wong Estimated delivery 3-12 business days Format Paperback Condition Brand New Description This thesis describes the authors pioneering efforts in the conceptualization and implementation of combined platinum-based immuno-chemotherapeutics, which represent a significant paradigm shift from the conventional approach of directly targeting cancer. Publisher Description This thesis describes the authors pioneering efforts in the conceptualization and implementation of combined platinum-based immuno-chemotherapeutics, which represent a significant paradigm shift from the conventional approach of directly targeting cancer. The work described has opened up a rich and largely unexplored area for platinum-based drug design, and ultimately paves the way for superior immuno-chemotherapeutics with better clinical outcome for patients. Historically, the contribution of the immune system to chemotherapy outcomes has been neglected, as anticancer drugs were believed to be immunosuppressive. However, this has been challenged by contemporary evidence suggesting that many chemotherapeutics, including platinum-based agents, stimulate the innate and/or adaptive immune system and that these "secret allies" contribute tangibly to clinical outcomes. A multi-pronged immuno-chemotherapeutic approach not only shrinks tumors, but more importantly, reactivate dormant immuneresponses to malignancies, eliminating residual cancer cells. Author Biography Daniel Wong was born in Singapore and graduated with honors from the National University of Singapore (NUS) in 2011. Encouraged by a positive undergraduate research experience, he then continued to complete his doctoral studies in NUS in 2015 under the guidance of Prof. Ang Wee Han, working mainly on the immuno-modulating effects of platinum agents for cancer therapy. In 2015, he joined Nanyang Technological University as a Research Fellow under the supervision of Prof. Par Nordlund, a renowned structural biologist. There, he employed structure-based drug design techniques against molecular targets in both immuno-oncology and malaria. At the same time, he is also experimenting with new progressive methodologies for simultaneous target and ligand discovery. Apart from research, Daniel likes mentoring students because of their infectious enthusiasm and he believes that the future rests upon them. Daniel is a recipient of the Wang Gungwu Medal (2016) for best PhD thesis in the Natural Sciences in NUS and the Springer Thesis Prize (2017). Details ISBN 981134194X ISBN-13 9789811341946 Title Rethinking Platinum Anticancer Drug Design: Towards Targeted and Immuno-chemotherapeutic Approaches Author Daniel Yuan Qiang Wong Format Paperback Year 2018 Pages 147 Publisher Springer Verlag, Singapore GE_Item_ID:158869298; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

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Rethinking Platinum Anticancer Drug Design: Towards Targeted and Immuno-chemothe

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Restocking Fee: No

Return shipping will be paid by: Buyer

All returns accepted: Returns Accepted

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ISBN-13: 9789811341946

Book Title: Rethinking Platinum Anticancer Drug Design: Towards Targeted and

Number of Pages: Xxx, 147 Pages

Publication Name: Rethinking Platinum Anticancer Drug Design : Towards Targeted and Immuno-Chemotherapeutic Approaches

Language: English

Publisher: Springer

Subject: Chemistry / Clinical, Oncology, Pharmacology, Biochemistry

Publication Year: 2018

Item Height: 0.4 in

Item Weight: 16 Oz

Type: Textbook

Subject Area: Science, Medical

Author: Daniel Yuan Qiang Wong

Item Length: 9.2 in

Item Width: 6.1 in

Series: Springer Theses Ser.

Format: Trade Paperback

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